Giant Cell Lesion and Central Giant Cell Granuloma of Jaw: A Brief Review

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Central Giant Cell Granuloma of the Jaw Bones: A Review

Central giant cell granuloma (CGCG) is an uncommon, benign, proliferative, and nonodontogenic lesion whose etiology is not defined. Thought to represent a reparative response to intrabony haemorrhage and inflammation, CGCG was once regarded as a reactive lesion. Central giant cell granuloma usually is an asymptomatic lesion, which may become evident during routine radiographic examination or as...

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Multifocal Central Giant Cell Granuloma - A Case Report

Central giant cell granuloma is a benign, aggressive neoplasm composed of multinucleated giant cells that almost exclusively occurs in the jaws though extra-gnathic incidence is rare.Multifocal CGCGs of the jaws are very rare and suggestive of systemic diseases such as hyperparathyroidism,an inherited syndrome such as Noonan-like multiple giant cell lesion syndrome or other disorders.Very few c...

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Correlation Between Immunohistochemical Profile of Giant Cell Granuloma with Pathogenesis and Biologic Behavior: A Review Article

Abstract: Background and Aim: Giant cell Granulomas (central and peripheral) are two fairly common lesions of the oral cavity with uncertain etiology and pathogenesis. As well, the reason for their different biologic behavior is not well understood yet. This study aimed to review the immunohistochemical profile of giant cell granuloma and its correlation with pathogenesis and biologic behavior....

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A Comparative Immunohistochemical Study of CD105 Expression in Peripheral and Central Giant Cell Granuloma

Introduction: Despite similar histopathological features, peripheral giant cell granuloma (PGCG) and central giant cell granuloma (CGCG) differ in their biological behavior. PGCG and CGCG are hemorrhagic/vascular lesions, clinically and microscopically. Angiogenesis is necessary for the growth and development of lesions and affects their clinical behavior. CD105 is a useful vascular marker for...

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Aggressive central giant cell granuloma mimicking giant cell tumor

Introduction: Giant cell granulomas (GCGs) of the jaws are lesions that arise either peripherally in periodontal ligament, mucoperiosteum, or centrally in the bone. Histologically, both peripheral and central giant cell granuloma (CGCG) are characterized by the presence of numerous multinucleated giant cells (MGCs) in a prominent fibrous stroma. CGCG are further categorized into aggressive and ...

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ژورنال

عنوان ژورنال: Annals of Applied Bio-Sciences

سال: 2017

ISSN: 2455-0396,2349-6991

DOI: 10.21276/aabs.2017.1315